Tehran University of Medical Sciences Journal of Medical Bacteriology 2251-8649 3 1-2 2015 10 13 17 21 EN Arezou Taherpour Department of Microbiology, Kurdistan University of Medical Sciences, Sanandaj, IR Iran. Ali Hashemi Department of Microbiology, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran. Fatemeh Fallah Department of Microbiology, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran. Soroor Erfani-Manesh Department of Microbiology, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran. Elahe Taki Department of Microbiology, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran. 2015 10 12 Background: The aim of this study was to determine the antibacterial activity of Zataria multiflora Boiss (Avishan-e Shirazi) and Carum copticum (Zenian) extracts on Vibrio cholerae American Type Culture Collection (ATCC14035)and V. cholerae Persian Type Culture Collection (PTCC1611) strains. Methods: Antimicrobial effects of the extracts were assayed by disc diffusion and broth microdilution methods. Results: Using susceptibility tests, it was shown that Carum copticum methanolic extract had the highest antibacterial effect on V. cholerae standard strains at 6.25 mg/ml concentration. Conclusions: Other evaluations considering herbal extracts as an antibacterial agent as well as in vivo examination of these extracts is needed to provide a natural, cost effective and strong alternative for traditionally less effective antibiotics normally used. https://jmb.tums.ac.ir/index.php/jmb/article/view/12 https://jmb.tums.ac.ir/index.php/jmb/article/download/12/48