Tehran University of Medical Sciences Journal of Medical Bacteriology 2251-8649 5 3-4 2017 01 13 41 44 EN Mohammad Amin Mashhady Department of Food Industry, Faculty of Agriculture, University of Zabol, Zabol, Iran. Barat Ali Fakheri Department of Plant Breeding and Biotechnology, Faculty of Agriculture, University of Zabol, Zabol, Iran. Saeide Saeidi Institute of Plant Biotechnology, Center of Agricultural Biotechnology, University of Zabol, Zabol, Iran. Mehdi Hassanshahian Department of Biology, Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman, Iran. Javad Abkhoo Institute of Plant Biotechnology, Center of Agricultural Biotechnology, University of Zabol, Zabol, Iran. 2017 01 13 2017 01 13 Background:  A large number of plants are used for treatment of diseases because of their antimicrobial activities. This study aims to investigate the antimicrobial effects of some plants on the food pathogenic bacteria.  Methods: Plant extracts were obtained using the rotary system, the minimum inhibitory concentration (MIC) by diluting method against bacteria was determined.  Results:  Results showed that the lowest MIC of the Peganum harmala was 3.1 ppm and the highest inhibitory concentration was 6.25 ppm for inhibiting the Vibrio cholerae. Conclusion:  The present study confirms the use of this extract as an antibacterial agent. Further research is required to evaluate the practical value of its therapeutic application. https://jmb.tums.ac.ir/index.php/jmb/article/view/254 https://jmb.tums.ac.ir/index.php/jmb/article/download/254/188