Tehran University of Medical Sciences Journal of Medical Bacteriology 2251-8649 3 3-4 2015 10 13 47 57 EN Hossein Esmaeili Department of Microbiology and Immunology, Faculty of Veterinary Medicine, University of Tehran, Tehran, IR Iran. 2015 10 12 2015 10 12 Brucellosis is a zoonotic disease that is widely distributed throughout the developing countries.In this review, an overview of the epidemiological and epizootic status of brucellosis in Islamic republic of Iran is presented. In Iran, the disease was first recognized in 1932, which is now endemic in the entire country. The first animal vaccination program was carried out in 1949. Brucellosis has been found in humans, cattle, sheep, goats, camels, horses, buffaloes, dogs and the prevalence of bovine brucellosis is estimated 0.3%. The successful implementation of a national brucellosis control program requires enough compensation, farmers’ cooperation, accurate diagnosis of infected animals and impetus of health system is required to overcome the disease. https://jmb.tums.ac.ir/index.php/jmb/article/view/44 https://jmb.tums.ac.ir/index.php/jmb/article/download/44/39