Tehran University of Medical Sciences Journal of Medical Bacteriology 2251-8649 13 4 2025 12 12 95 97 Mehdi Bakht Medical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran. Sara Rahimi Medical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran Hamid Sadeghi Medical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran Mohadeseh Khakpour Medical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran Maedeh Pourali Eshkalak Medical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran Farhad Nikkhahi Medical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran 2025 07 29 2025 08 28 Background:   Meningitis considered as one of the life-threatening diseases in humans which mainly caused by Neisseria meningitides. The onset of this bacterium can occur rapidly, and the disease progresses are quickly. Also, clinical symptoms of this disease emerge relatively late. For these reason, detection of this infection is difficult. This report explores using genosensors as a novel solution for the rapid diagnosis and detection of Neisseria meningitides. Conclusion:   Newly, for bacterial detection genosensors has been designed and used for diagnosis of some disease. Due to their simplicity, specificity, sensitivity, easy and convenient way to use, high accuracy, low detection time, use on site, and low cost it has been converted to a suitable way for rapid and accurate detection method for bacterial infection. https://jmb.tums.ac.ir/index.php/jmb/article/view/597