Journal of Medical Bacteriology 2014. 3(1-2):22-27.

Antimicrobial Effect of ZnSO4 on Multiple Drug Resistant Pseudomonas aeruginosa Strains
Mohammad Dadook, Sedigheh Mehrabian, Saeed Irian


Background: Due to the importance of the metal zinc as an essential biological element with known toxic properties, and considering the widespread secondary infections caused by Pseudomonas aeruginosa strains with resistance to antibiotics and disinfectants, the present study aimed at exploring the antimicrobial properties of the metal zinc in both
clinical and environmental multiple drug resistant (MDR) strains of P. aeruginosa. MDR in P. aeruginosa is defined as the resistance to several antibiotics.
Methods: Bacterial strains were cultured in cetrimide agar medium at 37 °C for 48 h. Strains were identified both morphologically and biochemically. MIC values of the metal zinc were reported using the broth microdilution method.
Results: A total of 84 strains were isolated and identified. MIC values for sensitive and MDR strains were reported at 20 and 130 ppm, respectively.
Conclusions: It was concluded that the metal zinc at concentrations greater than 130 ppmwill have an antimicrobial effect on all sensitive and MDR strains of P. aeruginosa.


Pseudomonas aeruginosa; Antibiotic; MDR

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