Journal of Medical Bacteriology 2016. 5(5-6):13-20.

Bloodstream Bacterial Pathogens and Their Antibiotic Resistance Patterns in Rasht, Iran
Abdol-rasoul Sobhani, Mahin Mallaei, Samaneh Kazemi

Abstract


Background: The increasing bloodstream infection mainly in developing countries is one of the most
important health care systems concern. And, the choice of antimicrobial treatment for septicemia is
often empirical and based on the knowledge of local antimicrobial activity patterns of the most
common bacteria causing such bloodstream infections. This study was carried to identify the
microbial profile in the blood culture isolates and their antibiotic susceptibility patterns.
Methods: This retrospective cross sectional study was done at Razi Hospital, Rasht, Iran over a period
of thirteen months from August 2012 to September 2013. Bacteria were identified by various
biochemical tests and antimicrobial susceptibility testing of the isolates was performed by KirbyBauer disc diffusion method.
Results: Out of 953 identified isolates, Gram-negative isolates 482 (50.58%) were followed by Grampositive isolates 471 (49.42%). Among Gram-positive organisms Staphylococcus epidermidis was the
highest with 255 (54%) records and in Gram-negative bacteria Pseudomonas spp. was highest with
241 (50%) records. There were 467 (49.0%) positive blood culture reports for males and 487 (51.0%)
for females. Pseudomonas spp. (134 reports) and S. epidermidis (162 reports) were the most common
pathogens in male and woman, respectively. In 15-44 years old age group, Pseudomonas spp. and in
45-75< years age group, S. epidermidis were identified as the most common. S. epidermidis isolates
were more resistant to Erythromycin, Oxacillin and Doxycycline. Pseudomonas spp. isolates had
more resistant to imipeneme, amikacin and cefalexin.
Conclusion:It can be concluded that bacterial resistance to antibiotics which used against bloodstream
infections can make complication in treatment of infection cause by these pathogens.

Keywords


Anti-Bacterial Agents; Blood-Borne Pathogens; Bacteria

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