Case Reports

Identification of KPC-Producing Pseudomonas aeruginosa and Acinetobacter baumannii in a Burned Infant: A Case Report

Abstract

The objective of this study was to determine the phenotypic characteristics of KPC-producing Pseudomonas aeruginosa and Acinetobacter baumannii isolates. A case report study was performed at a tertiary burn care centre in Tehran,  Iran.  Nine  isolates  of Pseudomonas  aeruginosa  and  Acinetobacter baumannii from a hospitalized case were isolated. The identity of isolates was confirmed and their antibiotic susceptibility testing was performed. Eight out of nine Pseudomonas aeruginosa and Acinetobacter baumannii isolates were resistant to Imipenem.  Three out of 8 imipenem  resistant isolates were also positive for KPC test. Findings of this study highlight the importance of implementation  of an effective infection control strategy in order to prevent and reduce the emergence and spread of gram negative Carbapenemase- producing organisms in Iran.

Pfeifer Y, Cullik A, Witte W. Resistance to cephalosporins and carbapenems in Gram- negative bacterial pathogens. Int J Med Microbiol 2010; 300 (6): 371-9.

Guidance: Infection Prevention and Control Measures for Healthcare Workers in All Healthcare Setting, Public Health Agency of Canada, 2010.

Sidjabat HE, Silveira F , Potoski BA, et al. Interspecies Spread of Klebsiella pneumoniae Carbapenemase Gene in a Single Patient. Clin Infect Dis 2009; 49 (11): 1736-8.

Rastegar Lari A, Azimi L, Rahbar M, et al. Phenotypic Detection of Klebsiella pneumoniae Carbapenemase in Burns Patients: First Report, Potos from Iran. 2012; in press.

Falagas ME, Karageorgopoulos DE, Nordmann P. Therapeutic options for infections with Entrobacteriaceae producing carbapenem- hydrolysing enzymes. Future Microbiol 2011; 6 (6): 653-66.

Roh KH, Lee Ch.k, Sohn JW, Song W, Yong D, Lee K. Isolation of a Klebsilla pneumonia Isolate of Sequence Type 258 Producing KPC-2 Carbapenemase in Korea. Korean J Lab Med 2011; 31: 298-301.

Yamane K. KPC carbapenemase producing gram- negative bacteria. Nihon Rinsho 2012; 70: 267-71.

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IssueVol 1 No 1-2 (2012) QRcode
SectionCase Reports
Keywords
Pseudomonas aeruginosa Acinetobacter baumannii Klebsiella pneumoniae

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Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
How to Cite
1.
Azimi L, Alaghehbandan R, Mohammadpoor M, Rastegar-Lari A. Identification of KPC-Producing Pseudomonas aeruginosa and Acinetobacter baumannii in a Burned Infant: A Case Report. J Med Bacteriol. 2015;1(1-2):46-49.