Prevalence and Multiple Drug Resistance of Shigella sonnei Isolated from Diarrheal Stool of Children
AbstractBackground: Science the discovery of antibiotic, the incidence of antibiotic resistance has been inevitable. Although there has been many study in these area but problem still exists. The aim of this research was to study the serotyping and multiple antibiotic resistance patterns of Shigella sonnei isolated from diarrheal stool of children. Methods: The stool samples of children from zero to fourteen years of age admitted at Children Medical Center in Tehran were tested over period of twelvemonth. Identification of isolates was carried out according to standard methods and the antibiotic susceptibility test was performed using Kirby Bauer disk method. Results: Of the 200 samples analyzed 6 (3%) were tested positive for Shigella sonnei. The antibiotic resistance patterns showed that all were résistance to tetracycline, streptomycin, clindamycin and cortimoxazol, and 66.7% of the samples had multiples resistance to above antibiotics. Conclusion: The results showed that multiple antibiotics resistance of Shigella sonnei is increasing, therefore awareness about the prevention by improved hygiene and proper medication are needed to reduce the burden of the preventable infectious diseases among young children.
WHO. Division of diarrhoeal and acute respiratory disease control. Rational management of diarrhoea in children. Essent Drugs Monit 1991; 11: 10-1.
Saeed A, Abd H, Sandstrom G. Microbial aetiology of acute diarrhoea in children under five years of age in Khartoum, Sudan. J Med Microbiol 2015; 64(4):432-37.
Yamashiro T, Nakasone N, Higa N, et al. Etiological study of diarrheal patients in Vientiane, Lao People's Democratic Republic. J Clin Microbiol 1998; 36(8): 2195-99.
Niyogi K, Saha MR, De SP. Enteropathogens associated with acute diarrhoeal diseases. Indian J Public Health 1994; 38(2): 29-32.
Sadeghabadi AF, Ajami A, Fadaei R, et al. Widespread antibiotic resistance of
diarrheagenic Escherichia coli and Shigella species. J Res Med Sci 2014; 19(1): 51-55.
Jafari F, Hamidian M, Rezadehbashi M, et al. Prevalence and antimicrobial resistance of diarrheagenic Escherichia coli and Shigella species associated with acute diarrhea in Tehran, Iran. Can J Infect Dis Med Microbiol 2009; 20(3): 56-62.
Al-Moyed KA, Harmal NS, Al-Harasy AH, et al. Increasing single and multi-antibiotic resistance in Shigella species isolated from shigellosis patients in Sana'a, Yemen. Saudi Med J. 2006; 27(8): 1157-60.
Velayati AA, Khadem Shariati F, Ghazisaeidi K. Ten-year review of Shigella isolated from Patients School of Public Health, Tehran University of Medical Sciences. Zanjan Univ Med Sci 1993; 2(1): 12-16.
Ranjbar R, Soltan Dallal MM, Pourshafie MR, et al. Fatality due to shigellosis with special reference to molecular analysis f Shigella sonnei strains isolated from the fatal cases. Iranian J Clinic Infec Dis 2010; 5(1): 36-39.
Ranjbar R, Pourshafie MR, Soltan-Dallal MM, et al. Fatality due to shigellosis with special reference to molecular analysis f Shigella sonnei strains isolated from the fatal cases. Iranian J Clinic Infec Dis 2010; 5(1): 36-39.
Soltan Dallal MM, Ranjbar R, Pourshafi MR. The study of antimicrobial resistance among Shigella flexneri strains isolated in Tehran, Iran. J Pediatr Infect Dis 2011; 6: 125–29.
Pazhani GP, Ramamurthy T, Mitra U, et al. Species diversity and antimicrobial resistance of Shigella spp. isolated between 2001 and 2004 from hospitalized children with diarrhoea in Kolkata (Calcutta), India, Epidemiol Infect 2005; 133(6): 1089-95.
Lee JC, Oh JY, Kim KS, et al. Antimicrobial resistance of Shigella sonnei in Korea during the last two decades, APMIS 2001; 109(3): 228-34.
Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing; 17th informational supplement.M100-S17. Clinical and Laboratory Standards Institute, Wayne, PA, 2007.
Cheng T, Shi X, Yong W, et al. Molecular typing of Shigella sonnei isolates circulating in Nanjing, China, 2007-2011. J Infect Dev Ctries 2014; 15; 8(12): 1525-32.
Koh XP, Chiou CS, Ajam N, et al. Characterization of Shigella sonnei in Malaysia, an increasingly prevalent etiologic agent of local shigellosis cases. BMC Infect Dis 2012 20; 12: 122.
DeLappe N, O'Halloran F, Fanning S, et al. Antimicrobial resistance and genetic diversity of Shigella sonnei isolates from western Ireland, an area of low incidence of infection. J Clin Microbiol 2003; 41(5): 1919-24.
Moyo SJ, Gro N, Matee MI, et al. Age specific etiological agents of diarrhoea in hospitalized children aged less than five years in Dares Salaam, Tanzania. BMC Pediatr 2011; 23: 11-19.
Mashoto KO, Malebo HM, Msisiri E, et al. Prevalence, one week incidence and knowledge on causes of diarrhea: household survey of under-fives and adults in Mkuranga district, Tanzania. BMC Public Health. 2014; 14: 985.
Klein EJ, Boster DR, Stapp JR, et al. etiology in a children’s hospital emergency department: a prospective cohort study. Clin Infect Dis 2006 1; 43(7): 807-13.
Shariff M, Deb M, Singh R. A study of diarrhoea among children in eastern Nepal with special reference to rotavirus. Indian J Med Microbiol 2003; 21(2): 87-90.
Sherchand JB, Yokoo M, Sherchand O, et al. Burden of enteropathogens associated diarrheal diseases in children hospital, Nepal. Sci World 2009; 7: 71–75.
Khorshidi A, Akhbari H, Salalehi A. Shigellosis frequency , serotyping & antibiotical resistance pattern in Kashan , Iran (2000-2001) Fezy J 2006; 40: 5-70.
Hoseini MJ, Nasri Razin B, Hoseini Doost R, et al. Antibiotic resistance among Shigella serotypes isolated from Shigella cases. Booali hospital, 1999-2001. Pajouhandeh 2003; 8(31): 35-8.
Iwalokun BA, Gboenle GO, Smith SI, et al. Epidemiology of Shigellosis in Lagos, Nigeria: trends in antimicrobial resistance. J Health Popul Nutr 2001; 19(3): 183-90.
Al-Moyed KA, Harmal NS, Al-Harasy AH, et al. Increasing signal and multi-antibiotic resistance in Shigella species isolated from shigellosis patients in Sana, Yemen. Saudi Med J 2006; 27(8): 1157-60.
Sivapalasingam S, Nelson JM, Joyce K, et al. High prevalence of antimicrobial resistance among Shigella isolates in the united states tested by the national antimicrobial resistance monitoring system from 1999 to 2002. Antimicrob Agents Chemother 2006; 50(1): 49-54.
Ebrahimi A, Ebrahimi S, Agholi M. Investigation on antibiotic resistance of Shigella species isolated from diarrheal children, Fasa. Iranian South Med J 2005; 12(3): 225-32.
Mohammadzadeh Moghimian M, Ebadi A, Shariatifar N. The study of antimicrobial resistance of Shigella strains isolated form diarrheal patients in Gonabad, Gonabad's 22-Bahman hospital, 2005-2006. Horizon Med Sci. 2008; 14 (1) :33-36
Van Gelderen de Komaid A, Runco de Laborda R, Salim R. Natural occurrence of Nocardia in soil of Tucumán: Physiological characteristics. Mycopathologia 1987; 99(1): 15-9.
|Issue||Vol 4 No 3-4 (2015)|
|Antibiotic Anti-microbial susceptibility Serology Shigella sonnei|
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