Study the Antimicrobial Effects of Momordica charantia on Pathogenic Bacteria
Abstract
Background: The aim of this study was to investigate the antimicrobial effects of Momordica charantia against pathogenic bacteria.
Methods: Extract of M. charantia species was extracted using Rotary device. Minimum Inhibitory Concentration (MIC) and Minimum Bacterial Concentration (MBC) of extract on mentioned bacteria were determined using micro dilution broth method at six different concentrations.
Results: The results of this study showed that the lowest inhibitory concentration of extract against bacteria was 12.5 ppm, (Vibrio cholera, Pseudomonas aeruginosa and E. coli) the results also showed that only one inhibited. However, the highest inhibitory concentration was estimated 25 ppm against Shigella dysenteriae and Bacillus cereus and highest bactericidal concentration was estimated 25 and 50 ppm.
Conclusion: The results of this study show good antimicrobial effects of M. charantia on pathogenic bacteria and these medicinal plants can be used to treat infections caused by bacteria.
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2. Mohsenipour Z, Hassanshahian, M. Antibacterial activity of Euphorbia hebecarpa alcoholic extracts against six human pathogenic bacteria in planktonic and biofilm forms. Jundishapur J Microbiol 2016; 9(6):e34701.
3. Sadeghian I, Hassanshahian, M, Sadeghian S, et al. antimicrobial effects of Quercus brantii fruits on bacterial pathogens. Jundishapur J Microbiol 2012; 5(3):465-69.
4. Mohammadi M, Masoumipour F, Hassanshahian M, et al. Study the antibacterial and antibiofilm activity of Carum copticum against antibiotic-resistant bacteria in planktonic and biofilm forms. Microbial Pathogen 2019; 129:99-105.
5. Saeidi S, Amini Boroujeni N, Ahmadi H, et
al. Antibacterial activity of some plant extracts against extended- spectrum beta-lactamase producing Escherichia coli isolates. Jundishapur J Microbiol 2015; 8(2):e15434.
6. Mohsenipour Z, Hassanshahian M. The inhibitory effect of Thymus vulgaris extracts on the planktonic form and biofilm structures of six human pathogenic bacteria. Avicenna J Phytomed 2015; 5(4):309-17.
7. Sepehri Z, Javadian F, Khammari D, et al. Antifungal effects of the aqueous and ethanolic leaf extracts of Echinophora platyloba and Rosmarinus officinalis. Curr Med Mycol 2016; 2(1):16-25.
8. Mohsenipour Z, Hassanshahian M, Moradi M. Investigations of antimicrobial activity of Eucalyptus camaldulensis extracts against six pathogenic bacteria in planktonic form and biofilm. J Kerman Uni Med 2015; 22 (2):172-84.
9. Masoumipour F, Hassanshahian M, Jafarinasab T. Antimicrobial activity of combined extracts of Trachyspermum, Thymus and Pistachio against some pathogenic bacteria. J Kerm Med Uni 2018; 25(2):153-63.
10. Omoregbe RE, Ikuebe OM, Ihimire IG. Antimicrobial activity of some medicinal plants extracts on Escherichia coli, Salmonella paratyphi and Shigella dysenteriae. African J of Med and Health Sci 1996; 25:373-5.
11. Prabakar K, Jebanesan A. Larvicidal efficacy of some Cucurbitacious plant leaf extracts against Culex quinquefasciatus (Say). Bio Tec 2004; 95:113-4.
12. Mada SB, Garba A, Mohammed HA, et al. Antimicrobial activity and phytochemical screening of aqueous and ethanol extracts of Momordica charantia leaves. J of Med Plants Res 2013; 7(10):579-86.
13. Jagessar RC, Mohamed A, Gomes G. An evaluation of the Antibacterial and
Antifungal activity of leaf extracts of Momordica Charantia against Candida albicans, Staphylococcus aureus and Escherichia coli. Nat Sci 2008; 6(1):1545-53.
14. Ankita S, Parminder K, Ruby G. Phytochemical screening and antimicrobial assay of various seeds extract of Cucurbitaceae family. Inter J of Applied Biology and Phar Tec 2012; 3(3):401-5.
15. Mwambete KD. The in vitro antimicrobial activity of fruit and leaf crude extracts of Momordica charantia: A Tanzania medicinal plant. African Health Sci 2009; 9(1):34-9.
16. Leelaprakash G, Caroline Rose J, Gowtham BM, et al. An invitro antimicrobial activity of Momordica Charantia leaves. Pharmacophore 2011; 2(4):207-15
17. Braca A, Siciliano T, D’Arrigo M, et al. Chemical composition and antimicrobial activity of Momordica charantia seed essential oil. Fitoterapia 2008; 79(2):123-5
18. De Lucena Filho JHS, de Freitas Lima R, de Medeiros ACD, et al. Antimicrobial potential of Momordica charantia L. against multiresistant standard species and clinical isolates. The J of Contemporary Den Pra 2015; 16(11):854-8.
19. Hassanshahian M, Bayat Z, Saeidi S, et al. Antimicrobial activity of Trachyspermum ammi essential oil against human bacterial”. Inter J Advan Biol Biomed Res 2014; 2(1): 18-24.
20. Saeidi S, Shiri Y, Bokaeian M, et al. Antibacterial activity of essential oil of satureja hortensis against multi-drug resistant bacteria. Inter J Enteric Path 2013; 2(2):1-4.
21. Bokaeian M, Sheikh M, Hassanshahian M, et al. The antibacterial activity of silver nanoparticles produced in the plant Sesamum indicum seed extract: a green method against multi-drug resistant Escherichia coli. Inter J
Enteric Path 2014; 2(2):e17928.
22. Rezaie Keikhaie K, Ghorbani S, Hosseinzadeh Z, et al. Antimicrobial activity of methanol extract of Citrullus colocynthis against antibiotic-resistant Staphylococcus aureus. Adv Herb Med 2017; 3(3):1-6.
23. Hassanshahian M, Khosravi F. Study the antimicrobial effects of Artemisia santonica extract on some pathogenic bacteria. Adv Herb Med 2015; 1(4):43-6.
24. Mohsenipour Z, Hassanshahian M. Antibacterial activity of Espand (Peganum harmala) alcoholic extracts against six pathogenic bacteria in planktonic and biofilm forms. Biol J Micro 2016; 4(16):47-57.
25. Javadian F, Sepehri Z, Saeedi S, et al. Antifungal effects of the extract of the Withania somnifera on Candida albicans. Adv Herb Med 2016; 2(1):32-43.
26. Hamayeli H, Shoshtari A, Hassanshahian M, et al. Study the antimicrobial activity of six marine sponges and three parts of sea anemone on Candida albicans. J Coastal Life Med 2016; 4(8):122-9.
27. Mashhadi M, Fakhri J, Saeedi S, et al. Antimicrobial effects of medicinal plants collected in Zabol, Iran, on pathogenic food pathogenic. J Med Bacteriol 2016; 5(3):18-28.
28. Jahani Z, Hosseinzadeh F, Shahi Z, et al. In vitro study of antimicrobial effects of Rosmarinus officinalis and Glycyrrhiza glabra extracts against some pathogens. Adv Herb Med 2016; 2(4):32-9.
29. Heydari F, Saeedi S, Hassanshahian M. Antibacterial activity of Mentha longifolia against Salmonella typhimurium. Adv Herb Med 2015; 1(3):42-7.
30. Mohsenipour Z, Hassanshahian M. Investigating the effectiveness of Centaureacyanus extracts on planktonic growth and biofilm structures of six
pathogenic bacteria. SSU Journals 2014; 22(4):1358-70.
31. Mohsenipour Z, Hassanshahian M. Inhibitory effects of Tamarix hispida extracts on planktonic form and biofilm formation of six pathogenic bacteria. Biol J Micro 2015; 4(13):25-36.
32. Sepehri Z, Hassanshahian M, Shahi Z, et al. Antibacterial effect of ethanol extract of Camellia sinensis l against Escherichia coli. Asian Pacific J Microbiol Res 2014; 2(1):6-8.
33. Rezaie Keikhaie K, Bagheri G, Hassanshahian M, et al. Antimicrobial effects of Zataria multiflora essential oils on Acinetobacter strains isolated from clinical specimens. J Herb Drug 2018; 8(4):251-6.
2. Mohsenipour Z, Hassanshahian, M. Antibacterial activity of Euphorbia hebecarpa alcoholic extracts against six human pathogenic bacteria in planktonic and biofilm forms. Jundishapur J Microbiol 2016; 9(6):e34701.
3. Sadeghian I, Hassanshahian, M, Sadeghian S, et al. antimicrobial effects of Quercus brantii fruits on bacterial pathogens. Jundishapur J Microbiol 2012; 5(3):465-69.
4. Mohammadi M, Masoumipour F, Hassanshahian M, et al. Study the antibacterial and antibiofilm activity of Carum copticum against antibiotic-resistant bacteria in planktonic and biofilm forms. Microbial Pathogen 2019; 129:99-105.
5. Saeidi S, Amini Boroujeni N, Ahmadi H, et
al. Antibacterial activity of some plant extracts against extended- spectrum beta-lactamase producing Escherichia coli isolates. Jundishapur J Microbiol 2015; 8(2):e15434.
6. Mohsenipour Z, Hassanshahian M. The inhibitory effect of Thymus vulgaris extracts on the planktonic form and biofilm structures of six human pathogenic bacteria. Avicenna J Phytomed 2015; 5(4):309-17.
7. Sepehri Z, Javadian F, Khammari D, et al. Antifungal effects of the aqueous and ethanolic leaf extracts of Echinophora platyloba and Rosmarinus officinalis. Curr Med Mycol 2016; 2(1):16-25.
8. Mohsenipour Z, Hassanshahian M, Moradi M. Investigations of antimicrobial activity of Eucalyptus camaldulensis extracts against six pathogenic bacteria in planktonic form and biofilm. J Kerman Uni Med 2015; 22 (2):172-84.
9. Masoumipour F, Hassanshahian M, Jafarinasab T. Antimicrobial activity of combined extracts of Trachyspermum, Thymus and Pistachio against some pathogenic bacteria. J Kerm Med Uni 2018; 25(2):153-63.
10. Omoregbe RE, Ikuebe OM, Ihimire IG. Antimicrobial activity of some medicinal plants extracts on Escherichia coli, Salmonella paratyphi and Shigella dysenteriae. African J of Med and Health Sci 1996; 25:373-5.
11. Prabakar K, Jebanesan A. Larvicidal efficacy of some Cucurbitacious plant leaf extracts against Culex quinquefasciatus (Say). Bio Tec 2004; 95:113-4.
12. Mada SB, Garba A, Mohammed HA, et al. Antimicrobial activity and phytochemical screening of aqueous and ethanol extracts of Momordica charantia leaves. J of Med Plants Res 2013; 7(10):579-86.
13. Jagessar RC, Mohamed A, Gomes G. An evaluation of the Antibacterial and
Antifungal activity of leaf extracts of Momordica Charantia against Candida albicans, Staphylococcus aureus and Escherichia coli. Nat Sci 2008; 6(1):1545-53.
14. Ankita S, Parminder K, Ruby G. Phytochemical screening and antimicrobial assay of various seeds extract of Cucurbitaceae family. Inter J of Applied Biology and Phar Tec 2012; 3(3):401-5.
15. Mwambete KD. The in vitro antimicrobial activity of fruit and leaf crude extracts of Momordica charantia: A Tanzania medicinal plant. African Health Sci 2009; 9(1):34-9.
16. Leelaprakash G, Caroline Rose J, Gowtham BM, et al. An invitro antimicrobial activity of Momordica Charantia leaves. Pharmacophore 2011; 2(4):207-15
17. Braca A, Siciliano T, D’Arrigo M, et al. Chemical composition and antimicrobial activity of Momordica charantia seed essential oil. Fitoterapia 2008; 79(2):123-5
18. De Lucena Filho JHS, de Freitas Lima R, de Medeiros ACD, et al. Antimicrobial potential of Momordica charantia L. against multiresistant standard species and clinical isolates. The J of Contemporary Den Pra 2015; 16(11):854-8.
19. Hassanshahian M, Bayat Z, Saeidi S, et al. Antimicrobial activity of Trachyspermum ammi essential oil against human bacterial”. Inter J Advan Biol Biomed Res 2014; 2(1): 18-24.
20. Saeidi S, Shiri Y, Bokaeian M, et al. Antibacterial activity of essential oil of satureja hortensis against multi-drug resistant bacteria. Inter J Enteric Path 2013; 2(2):1-4.
21. Bokaeian M, Sheikh M, Hassanshahian M, et al. The antibacterial activity of silver nanoparticles produced in the plant Sesamum indicum seed extract: a green method against multi-drug resistant Escherichia coli. Inter J
Enteric Path 2014; 2(2):e17928.
22. Rezaie Keikhaie K, Ghorbani S, Hosseinzadeh Z, et al. Antimicrobial activity of methanol extract of Citrullus colocynthis against antibiotic-resistant Staphylococcus aureus. Adv Herb Med 2017; 3(3):1-6.
23. Hassanshahian M, Khosravi F. Study the antimicrobial effects of Artemisia santonica extract on some pathogenic bacteria. Adv Herb Med 2015; 1(4):43-6.
24. Mohsenipour Z, Hassanshahian M. Antibacterial activity of Espand (Peganum harmala) alcoholic extracts against six pathogenic bacteria in planktonic and biofilm forms. Biol J Micro 2016; 4(16):47-57.
25. Javadian F, Sepehri Z, Saeedi S, et al. Antifungal effects of the extract of the Withania somnifera on Candida albicans. Adv Herb Med 2016; 2(1):32-43.
26. Hamayeli H, Shoshtari A, Hassanshahian M, et al. Study the antimicrobial activity of six marine sponges and three parts of sea anemone on Candida albicans. J Coastal Life Med 2016; 4(8):122-9.
27. Mashhadi M, Fakhri J, Saeedi S, et al. Antimicrobial effects of medicinal plants collected in Zabol, Iran, on pathogenic food pathogenic. J Med Bacteriol 2016; 5(3):18-28.
28. Jahani Z, Hosseinzadeh F, Shahi Z, et al. In vitro study of antimicrobial effects of Rosmarinus officinalis and Glycyrrhiza glabra extracts against some pathogens. Adv Herb Med 2016; 2(4):32-9.
29. Heydari F, Saeedi S, Hassanshahian M. Antibacterial activity of Mentha longifolia against Salmonella typhimurium. Adv Herb Med 2015; 1(3):42-7.
30. Mohsenipour Z, Hassanshahian M. Investigating the effectiveness of Centaureacyanus extracts on planktonic growth and biofilm structures of six
pathogenic bacteria. SSU Journals 2014; 22(4):1358-70.
31. Mohsenipour Z, Hassanshahian M. Inhibitory effects of Tamarix hispida extracts on planktonic form and biofilm formation of six pathogenic bacteria. Biol J Micro 2015; 4(13):25-36.
32. Sepehri Z, Hassanshahian M, Shahi Z, et al. Antibacterial effect of ethanol extract of Camellia sinensis l against Escherichia coli. Asian Pacific J Microbiol Res 2014; 2(1):6-8.
33. Rezaie Keikhaie K, Bagheri G, Hassanshahian M, et al. Antimicrobial effects of Zataria multiflora essential oils on Acinetobacter strains isolated from clinical specimens. J Herb Drug 2018; 8(4):251-6.
| Files | ||
| Issue | Vol 8 No 5-6 (2019) | |
| Section | Original Articles | |
| Keywords | ||
| Momordica charantia Plant extract Pathogenic bacteria. | ||
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How to Cite
1.
Saravani K, Javadian E, Mohsenbeygi M, Hassanshahian M. Study the Antimicrobial Effects of Momordica charantia on Pathogenic Bacteria. J Med Bacteriol. 2019;8(5-6):1-7.
